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© Cardiff University Department of Dermatology

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What dermoscopic features can you see?
Regression
Perifollicular hypopigmentation
Milia-like cysts
Pseudonetwork
Jelly sign
Brown globules




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FeaturesDiagnosis

Perifollicular hypopigmentation forming a psuedonetwork. The jelly sign is evident.
Regression
Perifollicular hypopigmentation
Milia-like cysts
Pseudonetwork
Jelly sign
Brown globules




Diagnosis

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What is your diagnosis?
Superficial basal cell carcinoma
Brown globular naevus
Solar lentigo
Lentigo maligna melanoma
Melanoma with regression
Naevus with regression
A solar lentigo showing perifollicular hypopigmentation to form a regular brown pseudonetwork, characterised by sharp demarcation at the periphery (the jelly sign).

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What dermoscopic features can you see?
Globules
Parallel-furrow pattern
Eccrine duct openings
Parallel-ridge pattern
Lattice pattern
Streaks




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FeaturesDiagnosis

Parallel-ridge pattern of pigmentation. Eccrine duct openings in the ridges. Greyish brown globules.
Globules
Parallel-furrow pattern
Eccrine duct openings
Parallel-ridge pattern
Lattice pattern
Streaks




Diagnosis

DiagnosisMain Menu

What is your diagnosis?
Acral naevus
Subcorneal haemorrhage
Spitz/reed naevus
Globular naevus
Acral melanoma
Lentigo maligna melanoma
This is an acral melanoma characterised by pigmented parallel lines located on the ridges (parallel-ridge pattern). Note that the ridges are thicker than the furrows. The eccrine duct openings are seen in the ridges. Brown-grey globules centrally signify that this is an invasive melanoma.

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What dermoscopic features can you see?
Grey pseudonetwork
Streaks
Pigmented follicular openings
Globular pattern
Maple-leaf structures
Rhomboidal structures




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FeaturesDiagnosis

Grey pseudonetwork, pigmented follicular openings with rhomboidal structures.
Grey pseudonetwork
Streaks
Pigmented follicular openings
Globular pattern
Maple-leaf structures
Rhomboidal structures




Diagnosis

DiagnosisMain Menu

What is your diagnosis?
Pigmented seborrhoeic keratosis
Solar lentigo
Melanoma in-situ
Basal cell carcinoma
Nodular melanoma
Junctional naevus
This is a lentigo maligna melanoma (melanoma in-situ) with a grey pseudonetwork made up of rhomboidal structures due to asymmetrical pigmentation of follicular openings.

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What dermoscopic features can you see?
Perifollicular hypopigmentation
Blue-white veil
Structureless white area
Pepper-like granules
Regression > 10% of lesion surface
Regression < 10% of lesion surface




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FeaturesDiagnosis

Regression > 10% of lesion surface with pepper-like granules
Perifollicular hypopigmentation
Blue-white veil
Structureless white area
Pepper-like granules
Regression > 10% of lesion surface
Regression < 10% of lesion surface




Diagnosis

DiagnosisMain Menu

What is your diagnosis?
Dermatofibroma
Naevus in type I skin
Melanoma
Seborrhoeic keratosis
Basal cell carcinoma
Squamous cell carcinoma
This is a melanoma. The most striking feature is the large area of regression composed of blue pepper-like granules over a white scar-like background, corresponding histopathologically to melanophages and fibrosis, respectively.

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FeaturesCheck Answers

What dermoscopic features can you see?
Structureless blue pigmentation
Pigment network
Globules
Black blotch
Central hypopigmentation
Pseudonetwork




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FeaturesDiagnosis

Central structureless blue pigmentation with a globular pattern peripherally.
Structureless blue pigmentation
Pigment network
Globules
Black blotch
Central hypopigmentation
Pseudonetwork




Diagnosis

DiagnosisMain Menu

What is your diagnosis?
Blue naevus
Globular naevus
Melanoma
Combined naevus
Pigmented basal cell carcinoma
Halo naevus
Two naevus cell populations are seen in this lesion. There is the blue naevus component seen as structureless blue pigmentation centrally and a globular-congenital naevus component peripherally. This is an example of a combined naevus.

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What dermoscopic features can you see?
Dotted vessels
Milky-red colour
Ulceration
Chrysalis structures
Arborizing vessles
Irregular vessels




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FeaturesDiagnosis

Dotted vessels, linear irregular and hairpin vessels. A milky-white colour, chrysalis structures and ulceration
Dotted vessels
Milky-red colour
Ulceration
Chrysalis structures
Arborizing vessles
Irregular vessels




Diagnosis

DiagnosisMain Menu

What is your diagnosis?
Spitz / reed naevus
Basal cell carcinoma
Squamous cell carcinoma
Melanoma
Bowen’s disease
Cherry angioma
This is an amelanotic melanoma, showing the typical pink - milky red colour. Polymorphous vessels which include scattered dotted, linear-irregular and hairpin vessels are seen. In addition, white orthogonal lines representing chrysalis structures are seen in the upper part of the lesion indicated by the white arrows.

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What dermoscopic features can you see?
Pigment network
Streaks
Globules
Blue white structures
Comedo-like openings
Black dots




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FeaturesDiagnosis

Peripheral globules, blue white structures, black dots in the centre, and pigment network.
Pigment network
Streaks
Globules
Blue white structures
Comedo-like openings
Black dots




Diagnosis

DiagnosisMain Menu

What is your diagnosis?
Globular naevus
Spitz/Reed naevus
Melanoma
Reticular neavus
Pigmented basal cell carcinoma
Compound naevus
In this melanoma, remnants of a pigment network with asymmetrically distributed peripheral globules (a sign of growth) and blue white structures are seen. Centrally there are few black dots in a rather structureless brown area.

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FeaturesCheck Answers

What dermoscopic features can you see?
Dotted vessels
Arborizing vessels
Negative pigment network
Pseudonetwork
Grey-blue areas
Linear irregular vessels




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FeaturesDiagnosis

Regularly distributed dotted vessels and linear irregular vessels in the centre.
Dotted vessels
Arborizing vessels
Negative pigment network
Pseudonetwork
Grey-blue areas
Linear irregular vessels




Diagnosis

DiagnosisMain Menu

What is your diagnosis?
Globular naevus
Bowen’s disease
Spitz/Reed naevus
Basal cell carcinoma
Spitzoid Melanoma
Irritated seborrhoeic keratosis

This lesion appears “spitzoid” due to predominant presence of regularly distributed dotted vessels surrounded by a reticular depigmentation (negative pigment network). In the central area some linear irregular vessels can be seen. The diagnosis of a melanocytic lesion is facilitated by the presence of brown pigmentation. The diagnosis is spitzoid melanoma.

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What dermoscopic features can you see?
Multiple milia cysts
Pigment network with asymmetric
pattern and abrupt edge
Pseudopods
Pigment network with symmetric
pattern and graduated edge
Radial streaming
Crypts




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FeaturesDiagnosis

Pigment network with symmetric pattern and graduated edge can be seen on the image.
Multiple milia cysts
Pigment network with asymmetric
pattern and abrupt edge
Pseudopods
Pigment network with symmetric
pattern and graduated edge
Radial streaming
Crypts




Diagnosis

DiagnosisMain Menu

What is your diagnosis?
Melanoma
Seborrhoeic keratosis
Benign melanocytic (junctional) naevus
Ink-spot lentigo
Solar lentigo
Under the dermatoscope, junctional naevi have a symmetric pigment network with thin lines and with holes of fairly regular size. They are typically tan or brown in colour and the edge fades away gradually into the surrounding skin.

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